Biological Functions Of Estrogen

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Reproductive Immunology: Open Access is an open access peer-reviewed journal with successful completion of three volumes welcomes submissions covering the wide variety of topics including immune infertility, gametogenesis, embryogenesis, immunological testing, implantation and placental development, autoimmunity, male and female reproductive tract, gestation and parturition, gametogenesis and embryogenesis, implantation and placental development, mammary glands and lactation, cancer reproductive immunology, etc. The actions of estrogen are mediated by the estrogen receptor (ER), a dimeric nuclear protein that binds to DNA and controls gene expression. Like other steroid hormones, estrogen enters passively into the cell where it binds to and activates the estrogen receptor. The estrogen: ER complex binds to specific DNA sequences called a hormone response element to activate the transcription of target genes (in a study using an estrogen-dependent breast cancer cell line as model, 89 such genes were identified). Since estrogen enters all cells, its actions are dependent on the presence of the ER in the cell. The ER is expressed in specific tissues including the ovary, uterus and breast. The metabolic effects of estrogen in postmenopausal women has been linked to the genetic polymorphism of the ER. While estrogens are present in both men and women, they are usually present at significantly higher levels in women of reproductive age. They promote the development of female secondary sexual characteristics, such as breasts, and are also involved in the thickening of the endometrium and other aspects of regulating the menstrual cycle. In males, estrogen regulates certain functions of the reproductive system important to the maturation of sperm and may be necessary for a healthy libido Our Journal emphasizes high-level research and education. Original research articles, reviews, short communications, and letters to the editors in the field of Reproductive Immunology are welcome. Every effort is made to have a speedy and critical peer-review process. We always encourage new research works under the scope of our Journal. Regards, Rose Marie Reproductive Immunology: Open Access Email: reprodimmunol@emedsci.com Whatsapp no: +1-947-333-4405