Immunological disorder

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Immunological disorder occurs due to malfunctioning of the immune system. This disorder can be distinguished in several different ways: By the component(s) of the immune system affected; By whether the immune system is overactive or underactive; By whether the condition is congenital or acquired.

An immune disorder is a dysfunction of the immune system. These disorders can be characterized in several different ways:

By the component(s) of the immune system affected

By whether the immune system is overactive or underactive

By whether the condition is congenital or acquired

According to the International Union of Immunological Societies, more than 150 primary immunodeficiency diseases (PIDs) have been characterized.[1] However, the number of acquired immunodeficiencies exceeds the number of PIDs.

It has been suggested that most people have at least one primary immunodeficiency.[3] Due to redundancies in the immune system, though, many of these are never detected.

Autoimmune diseases

An autoimmune disease is a condition arising from an abnormal immune response to a normal body part. There are at least 80 types of autoimmune diseases. Nearly any body part can be involved. Common symptoms include low-grade fever and feeling tired.Often symptoms come and go.

  • List of some autoimmune disorders
  • Main article: Autoimmune disease
  • Lupus
  • Scleroderma
  • Certain types of hemolytic anemia
  • Vasculitis
  • Type 1 diabetes
  • Graves' disease
  • Rheumatoid arthritis
  • Multiple sclerosis (although it is thought to be an immune-mediated process)
  • Goodpasture syndrome
  • Pernicious anemia
  • Some types of myopathy
  • Lyme disease (Late)
  • Immunodeficiencies

Primary immune deficiency diseases are those caused by inherited genetic mutations. Secondary or acquired immune deficiencies are caused by something outside the body such as a virus or immune suppressing drugs.

Primary immune diseases are at risk to an increased susceptibility to, and often recurrent ear infections, pneumonia, bronchitis, sinusitis or skin infections. Immunodeficient patients may less frequently develop abscesses of their internal organs, autoimmune or rheumatologic and gastrointestinal problems.

Media Contacts,
Managing Editor
Rutherford
Journal of Autoimmune Disorders